Hyperhidrosis is a very common condition and there are many treatments to choose from, including antiperspirants, iontophoresis, Botox, surgery and oral drugs. But what exactly are these new medications? And what are their side effects? In this article, you'll learn more about the treatments and new drugs for hyperhidrosis called anticholinergics.

Treatment options 

If you have excessive sweating, there are treatment options that you may not have considered. Symptoms vary from mild to severe, but they can interfere with your daily activities. Some treatment options involve surgery. 

Your primary care provider may refer you to a dermatologist, who will determine a treatment plan that's right for your unique situation. Other medical specialists may be necessary, including a neurologist and a surgeon. To ensure that you receive the best treatment, make sure you know everything you can about your hyperhidrosis and your family history.

Benzodiazepines and beta-blockers can help manage your symptoms. These drugs act on the central nervous system and help you reduce your heart rate and body temperature. Some types of benzodiazepines are also effective in reducing sweating, especially when people are nervous or agitated. You should take these medications for at least 30-60 minutes prior to your scheduled event.

Fortunately, treatment options for hyperhidrosis are becoming more popular. You might even find a cure for your condition that you've never even heard of! Many people have successfully treated their condition with medication, and other treatments are becoming available today. 

Natural treatments for Excessive Sweating

If you suffer from hyperhidrosis, you may  have heard about sage. It has antibacterial and antiseptic properties, so it can reduce sweat production and smell. It is also a great moisturizing agent. Whether used topically or applied to the affected area, sage is a natural treatment for hyperhidrosis. However, this treatment can lead to unpleasant side effects, so you should consult a doctor before trying it.

Excessive sweating can cause emotional distress and disrupt daily life. Treatments may include meditation, exercise, or biofeedback. While some people swear by these methods, there are also those who still prefer traditional treatments. Here are some of the most effective treatments:

Biofeedback therapy has also been proven to be an effective treatment for hyperhidrosis. A patient will be able to see improvements in the condition after just a few sessions. Another method is homeopathy. This alternative approach to medicine was first developed in 1796. Homeopathic doctors believe that the body can heal itself if it is exposed to similar symptoms. Some of the remedies recommended by homeopathic doctors are sulfur, Calcarea carbonica, silica, lycopodium, and Ignatia. Homeopathic doses can be as small as a sugar pellet.

Although these treatments are very effective, they are expensive. Many people opt to use antiperspirants or Botox to help control their sweat. While these treatments can help control the sweating symptoms, they can have side effects and cause severe health issues. For example, the side effects of these drugs include blurred vision, heart palpitations, dry mouth, and trouble peeing. Surgical treatment may be an option for extreme cases of hyperhidrosis.

Surgical treatments

Surgical treatments for hyperhidrosis can be effective in many cases. A sympathetic thoracoscopic sympathectomy destroys the sympathetic nerve trunk, thereby reducing the severity of hyperhidrosis in a specific location and relieving associated symptoms. There are some risks associated with this procedure, however, including excessive bleeding and injury to surrounding organs. Patients with severe cardiovascular conditions and active infections, or those with previous chest surgeries, should not undergo this surgery.

Surgical treatments for hyperhidrosis can include excision of the sweat glands, sympathetic blockade, or local liposuction. The latter involves altering the communication between the sympathetic nervous system and the eccrine sweat glands. While there are many risks associated with surgery, it is usually the last resort. Non-surgical treatments, such as anticholinergics, aluminum chloride, or botulinum toxin, can be very effective. However, if none of these approaches are effective, surgical procedures may be an option.

A surgical procedure can be an effective treatment for hyperhidrosis if other methods have failed. The procedure is performed under general anesthesia and involves a small incision made under the arm. An endoscope is then inserted through the incision and identified as the source of the sweat glands' problem. The surgeon then cuts or clipped the affected nerves. The entire procedure can last for one to three hours.

Anticholinergics for Hyperhidrosis

If you have been looking for an effective treatment for your excessive sweating, anticholinergics may be the answer. These medications work on a systemic level to reduce sweating across the entire body, reducing the chances of overheating and overdrying in areas with sweat gland dysfunction. There are several different types of anticholinergics, including glycopyrrolate and oxybutynin.

However, these drugs have some side effects. They can cause dizziness, cramping, urinary retention, dry mouth, and dry eyes. Anticholinergics should be used with caution in patients with certain conditions and are not recommended for elderly individuals and active individuals. They can also lead to dehydration. These side effects should be considered carefully before starting anticholinergic treatment for hyperhidrosis.

Another drug that can be used to treat hyperhidrosis is oxybutynin, which is effective at reducing sweating. While this medication has some side effects, it is generally considered a safe, effective treatment for excessive sweating. While it may not be the right treatment for your problem, it can help improve your quality of life. 

Glycopyrronium tosylate (Glycopyrrolate)

Glycopyrronium tosylate is an anticholinergic agent that treats excessive underarm sweating, which is a common symptom of hyperhidrosis. The drug is a once-daily tablet that inhibits the interaction of acetylcholine with cholinergic receptors. Several factors may affect its delivery, including occlusion, exposure time, and skin thickness.

In the clinical trial, the treatment significantly reduced sweat production by 50% or more, compared to baseline. Sweat was measured gravimetrically in both axillae, and data were analyzed using the Markov chain Monte Carlo method to correct for multiple missing measurements. 

Despite the positive results of this clinical trial, a number of risks were associated with the use of this drug. One side effect was moderate unilateral mydriasis. Another was mild to moderate dehydration. One patient experienced a rash after application, while another reported urinary retention. Although the drug was not associated with a severe allergic reaction.

Oxybutynin and Pilocarpine

Oxybutynin and pilocaropine for hyperhidrosis offer patients an effective treatment for excessive sweating and dry mouth. The granules and multilayer beads contain 7.5 mg of each drug each. 

The granules contain oxybutynin HCl (89.9 mg) in a delayed-onset, immediate-release, and sustained-release form. The pilocarpine HCl beads were coated with oxybutynin HCl and enclosed in size 0-gelatin capsules. This granule was also formulated to be highly concentrated.

The oxybutynin and pilocardine for hyperhidrosis product has been approved by the FDA for the treatment of excessive sweating. It is not a cure for hyperhidrosis. It will not eliminate the condition, but it will improve symptoms and reduce the severity. It will also inhibit or stop its underlying pathology.